INFORMATION
Revanesse® Contour™+ with Lidocaine is a cross-linked hyaluronic acid gel used for the correction of facial wrinkles, lipoatrophy, and volume restoration. This product is designed for facial contouring, providing a solution for medium to deep facial rhytides and other soft tissue deficiencies. The product contains 25 mg/ml of cross-linked hyaluronic acid and 0.3% lidocaine for pain relief during application. It is presented as a colorless, odorless, and transparent gel in 1.2 ml pre-filled syringes.
Revanesse® Contour™+ with Lidocaine Indications for Use
Revanesse® Contour™+ is indicated for:
Restoration of facial volume and contour deficiencies in areas affected by lipoatrophy or lipodystrophy.
Treatment of facial rhytides (wrinkles) by injecting the product into the dermis.
Facial contouring and skin hydration.
Lip augmentation and treatment of moderate to severe facial wrinkles.
Intended Use:
Cosmetic improvements such as enhancing facial features, lifting skin, and restoring volume lost due to aging or medical conditions such as HIV-associated lipoatrophy.
Revanesse® Contour™+ with Lidocaine Dosage Information
Each syringe contains 1.2 ml of the product.
Injection should be done slowly, and minimal pressure should be applied.
Use only the provided 27G needle to ensure accurate and safe application.
The product must be stored at room temperature for at least 30 minutes before injection.
Limit of 20 ml per 60 kg of body weight per year for lidocaine content to minimize potential toxicity risks.
Revanesse® Contour™+ with Lidocaine Side Effects and Precautions
Physicians must inform patients of potential side effects that may occur either immediately or delayed after the injection. The most common side effects include:
Transient erythema (redness), swelling, pain, itching, and tenderness at the injection site. These usually resolve within one week.
Possible formation of nodules or induration at the injection site.
In some cases, hypersensitivity reactions may occur, including prolonged erythema and swelling, typically resolving after about two weeks.
Serious side effects to watch for include:
Glabellar necrosis, abscess formation, granulomas, and hypersensitivity reactions associated with hyaluronic acid products.
Intravascular injection may cause vascular occlusion, leading to embolism, ischemia, or infarction.
Temporary or permanent vision impairment has been reported due to intravascular injections, especially near high vascularity areas like the glabella or nose.
Patients with multiple allergies, auto-immune disorders, or those on immunotherapy should not use Revanesse® Contour™+.
Contraindications
Revanesse® Contour™+ should not be used in patients with:
Allergies to lidocaine or amide-type local anesthetics.
A history of hypertrophic scarring.
Pregnant or breastfeeding women.
Active acne, inflammatory skin diseases, or autoimmune conditions.
Patients undergoing anticoagulant therapy or with coagulation defects.
Previous treatment with permanent fillers or implants in the target area.
Individuals under 18 years old or above 65 years old.
Avoid injections near the eye area, as the product must not be injected into blood vessels, which could lead to serious complications, including embolisms.
Revanesse® Contour™+ with Lidocaine Drug Interactions
There are no specific drug interactions noted, but special care is needed for patients:
On anticoagulant therapy, aspirin, NSAIDs, or St. John’s Wort, as these may increase the risk of bruising or bleeding at the injection site.
With liver disease, epilepsy, or renal impairment, where the lidocaine content may pose additional risks.
Revanesse® Contour™+ with Lidocaine Clinical Studies or Outcomes
Revanesse® Contour™+ has been shown to effectively restore facial volume and enhance facial contours. The effects typically last 6 to 12 months, depending on the depth and location of the injection. Most patients experience significant improvement in facial volume and reduced visibility of wrinkles, contributing to a more youthful appearance. Patient satisfaction is generally high, with minimal side effects reported when applied correctly by trained professionals.
Revanesse® Contour™+ with Lidocaine Administration Instructions
Only trained physicians should perform injections, ensuring a sterile environment and proper technique.
Do not re-use needles or syringes to avoid infection risks.
Inject slowly and apply minimal pressure.
If blanching of the skin occurs (indicating a vascular occlusion), immediately stop the injection and massage the area until normal skin color returns.
Press the syringe plunger gently until a small drop is visible at the needle tip before injection.
Storage Instructions
Store the product between 2°C – 25°C, avoiding direct sunlight and freezing.
The shelf life of each package is indicated on the label.
Precautions
Avoid injecting into areas already treated with other fillers or areas containing permanent fillers.
Avoid exposure to intense heat (sunbathing, tanning beds) and extreme cold for several days post-treatment.
Patients with a history of cold sores should be informed that injection may trigger an outbreak.
Ensure thorough disinfection before the procedure.






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