INFORMATION
Product Description
STYLAGE® XXL BI-SOFT® Indications for Use
STYLAGE® XXL BI-SOFT® is an injectable gel composed of cross-linked hyaluronic acid. It is designed for the restoration or augmentation of facial volume, particularly for areas requiring large volume restoration. The product can be injected into the deep dermis or subcutaneous layers.
Key Indications: Facial volume restoration (e.g., cheeks, chin)
Area of Application: Deep dermis or subcutaneous injections
Product Components: Cross-linked hyaluronic acid and mannitol (antioxidant)
STYLAGE® XXL BI-SOFT® Dosage Information
The dosage of STYLAGE® XXL BI-SOFT® depends on the severity of the volume loss and the area being treated.
Recommended Dosage: Do not exceed 2.0 ml per treated area per session and a maximum of 20 ml of hyaluronic acid per year per patient.
Injection Frequency: Typically, 1-2 sessions are required for optimal correction, with touch-up treatments to maintain results.
Product Format: Available in pre-filled syringes of 1 ml or 2.2 ml.
STYLAGE® XXL BI-SOFT® Side Effects and Precautions
Common side effects include local inflammatory reactions, such as redness, swelling, and pain at the injection site. More severe but rare complications can include necrosis, abscesses, and granulomas.
Contraindications:
Do not use in: Areas with thin skin (e.g., forehead, eyes), vascular-rich areas, or lips.
Allergic reactions: Patients with a known hypersensitivity to hyaluronic acid or mannitol should avoid use.
Pregnancy and breastfeeding: Not recommended for women who are pregnant or nursing.
Precautions:
Avoid combining with treatments like peels, laser treatments, or dermabrasion without consulting a practitioner.
Patients with autoimmune diseases should be treated with caution and monitored closely.
Individuals with history of herpes may have a recurrence triggered by needle punctures.
STYLAGE® XXL BI-SOFT® Clinical Studies and Real-World Outcomes
The product is reported to provide long-lasting results due to its cross-linked hyaluronic acid formula, which is slowly absorbed by the body. The duration of effect depends on the patient’s skin type, injection depth, and area treated. Results typically last 6-12 months. Real-world evidence suggests that touch-up sessions prolong the desired outcomes.
STYLAGE® XXL BI-SOFT® Drug Interactions
There are specific interactions to consider:
Local anesthetics: STYLAGE® XXL contains lidocaine (optional), and should not be used in patients with known sensitivity to lidocaine or other amide-type local anesthetics.
Anticoagulants: Patients using aspirin, NSAIDs, or blood thinners should avoid these medications one week before injection to reduce the risk of hematomas.
Hepatic metabolism inhibitors: Avoid combining with drugs that inhibit liver metabolism.
STYLAGE® XXL BI-SOFT® Patient Aftercare and Recommendations
No massage: Refrain from massaging or pressing the treated area for 3 days after the injection.
Sun protection: Use a high-SPF sunscreen for two weeks post-treatment.
Avoid makeup: For 12 hours post-injection, avoid applying makeup.
Extreme conditions: Avoid exposure to extreme heat or cold (e.g., saunas, UV light) until swelling and redness subside.






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